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bp0005rdr15 | Pre-natal Programming of Lifetime Productivity and Health | REDR2002

Consequences of intra-uterine growth retardation for postnatal growth, metabolism and pathophysiology

Greenwood PL , Bell AW

Intra-uterine growth retardation (IUGR), caused by maternal undernutrition or placental insufficiency, is usually associated with disproportionately large reductions in the growth of some fetal organs and tissues (thymus, liver, spleen, thyroid) and impaired cellular development of other tissues (small intestine, secondary wool follicles, skeletal muscle). Growth of other tissues, most notably brain, is relatively unimpaired. In our recent study of postnatal consequences of IU...